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More than 85 pathologies treated with stem cells
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What are stem cells?
Numerous natural roles:
The natural role of the stem cells is: - to replace the degenerating cells, ensuring natural cell renewal; - to contribute to the growth of tissues and organs; - to repair damaged tissues, following a trauma, ischaemia or simply during the ageing process.
Two types of stem cells
Haematopoietic stem cells and mesenchymal stem cellsAdult stem cells are differentiated into two main types: haematopoietic and mesenchymal.
Adult haematopoietic stem cells specialise into blood cells: white blood cells, red blood cells and platelets.
Adult mesenchymal cells specialise into a multitude of cells constituting for example muscular, cartilaginous, boney, connective or adipose tissue.
Learn more about
Stem Cells
Clinicians throughout the world evaluate the efficiency of new cellular therapies and more than 5000 clinical studies are underway.
Stem cells are cells which have not yet been differentiated or specialised to perform a permanent and specific function. They have both the capacity to renew and to differentiate themselves into several types of cells depending on the requirements of our body.
Embryonic stem cells and adult stem cells
Stem cells are not all the same – there is a fundamental distinction between embryonic stem cells and adult stem cells. Embryonic stem cells, present in the embryo of one week, are capable of producing all types of different cells which are found in our bodies (totipotent stem cells). Their use is not ethical as the extraction of an embryonic stem cell leads to the destruction of the embryo itself.
Whereas adult stem cells, present in certain tissues and organs, can give rise to different specific cell types (multipotent or pluripotent stem cells) or give rise to a specific type of cell (unipotent stem cells). Contrary to the use of embryonic stem cells, cells of adult stem cells do not pose any ethical problem as they are not derived from destroyed human embryos.
Haematopoietic stem cells and mesenchymal stem cells
Adult stem cells are differentiated into two main types: haematopoietic and mesenchymal.
Adult haematopoietic stem cells specialise into blood cells: white blood cells, red blood cells and platelets.
Adult mesenchymal cells specialise into a multitude of cells constituting for example muscular, cartilaginous, boney, connective or adipose tissue.
Where are the stem cells found? There are different types of stem cells present in nearly all tissue. Nevertheless, some parts of the human body are particularly interesting sources for medicine.
The three main sources are:
- bone marrow,
- umbilical cord,
- adipose tissue.
Bone marrow was the first source discovered and it has been used for 60 years. At the end of the eighties, umbilical cord blood proved in its turn to be an extremely rich source of rich haematopoietic stem cells which present very high therapeutic qualities and incomparable accessibility. The collection of umbilical cord stem cells is in fact totally devoid of risk and is carried out in a simple manner. This explains why over the last 30 years this alternative to bone marrow is being used more and more. Furthermore, in comparison with haematopoietic stem cells of bone marrow donors, haematopoietic stem cells of the umbilical cord blood seem to cause less immune rejection or a graft-versus-host disease complication. Therefore, cord blood does not need to be perfectly compatible with the patient, contrary to bone marrow.
Other stem cells which present different properties in addition to those of the umbilical cord have also since been discovered and are starting to be used as for example adipose tissue and Wharton’s jelly enveloping the umbilical cord tissue (mesenchymal stem cells).
- the number of diseases which will be treatable using haematopoietic and mesenchymal stem cells will increase:
- the cellular therapies will replace or supplement certain treatments applied routinely today;
- cellular therapies will make it possible to treat diseases which are still incurable today.
- Cerebral palsy
- Type 1 diabetes
- Respiratory stress pathologies in premature babies (anaemia),
- Autism
- Cardiological pathologies (hypoplastic left heart syndrome)
- Acquired hearing loss
- Genetic treatment for genetic pathologies
- Lymphoid leukaemia and multiple myeloma
- Anaemia
- Ischemic stroke
- Bone defects and problems in healing fractures
- Rheumatoid arthritis
- Multiple sclerosis
- Myocardium regeneration in the case of infarction
- Reconstruction of the damaged spinal cord following trauma
- Treatment of neurodegenerative diseases (Parkinson and Alzheimer’s disease)
- Treatment of skeletal muscle disorders
- Treatment of degenerative diseases of the liver, kidneys, retina, cornea, hearing
- Treatment of metabolic diseases (for example diabetes)
- Boney reconstruction
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FAQs
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FAQs zur Lagerung und dem Vorgehen
Your samples will be processed as soon as they arrive in the laboratory following the highest quality standards.
The laboratory processes 6 days a week, 52 weeks a year, compliant with the guidelines, guaranteeing the best results to the client.
Your child’s blood and cord blood samples will be processed and stored in a specialised facility based exclusively in Switzerland.
All storage tanks have an individual security system and are monitored 24 hours a day, 365 days a year.
We hope you will never need it, but if it were to be, it will be our care to follow you along this path. If you need the stem cells for a therapeutic treatment, we will release the samples free of charge.
After agreeing the consent documents with you, we will agree with your doctor to arrange the safe delivery of the samples to the transplant centre indicated at the requested date and time.
The collection of blood and / or tissue of the anatomical tract of the umbilical cord does not interfere with the birth stages, nor does it alter the procedures with which the medical staff give birth to the child.
No. Whether you opt for a natural birth, a caesarean section or an induced delivery, there should be no problem collecting your child’s stem cells.
We always advise the medical staff to perform the withdrawal in the first minute after delivery. Any action performed after this time limit may affect the amount of cord blood available.
In any part of the world you live, the preservation of your samples at Nescens Swiss Stem Cell Science (Switzerland) will always be guaranteed.
In the event of a transfer, please remember to inform us of your new address and contact information so that we can keep your data up-to-date.
Your child’s stem cells can be used by anyone with a histocompatibility of at least 80%, such as a brother or sister. Stem cells of a relative (preferably brother/sister) are generally the first transplant option when considering the source of stem cells. In most allogeneic transplants (recipient other than donor) stem cells from a family member are used.
In Switzerland,. there are several hospitals where you can choose to donate umbilical cord blood stem cells to the public banks system.
The umbilical cord blood stem cells could be used to treat someone else around the world. However, you will no longer have direct access to this precious sample. For more information, please contact the Swiss Italian Blood Transfusion Center (CRS).
FAQs about STEM CELLS
Stem cells are not yet specialised, primitive cells, with the extraordinary ability to self-renew and differentiate into a multitude of cells. They create a direct link between the health of the child when it is born and the future.
If the child were to have any age-old health problem, stem cells can be the key to restoring their health.
Cord blood stem cells are already used in the treatment of over 80 diseases including leukaemia, anaemia and thalassaemia, with a constantly growing list. Those of the cordon tissue instead contribute to the growth, regeneration and repair of damaged tissues.
It is advisable to conserve stem cells for each child individually in order to ensure that you have a sample available with 100% compatibility for each of your children.
It is scientifically proven that there is a 25% probability of compatibility between brothers and sisters.
A cord blood sample should be between 20 and 60 ml, although this may differ greatly due to the size of the umbilical cord itself and the birth circumstances.
The sample must contain a minimum number of stem cells CD34+ to allow us to consider it suitable for a possible future therapeutic treatment. If your cord blood sample does not meet this requirement, you will have the option to refuse storage.
Currently, cord blood stem cells can be used to treat a wide range of diseases (more than 80), including:
- Red blood cell proliferation disorders (Anaemia, platelet disorders and others)
- Hereditary disorders of the immune system (severe combined immunodeficiency, neutropenia and others)
- Cancer (leukaemia, bone marrow cancer and more)
- Hereditary metabolic disorders (mucopolysaccharidosis accumulation diseases, leukodystrophy disorders, etc.)
Hereditary disorders affecting the immune system and other organs (hair hypoplasia, Gunther’s disease)
The laboratory has a time limit of 68 hours for the samples to arrive in the laboratory. Samples must be subjected to the separation procedure within 72 hours of birth.
After choosing the desired service, you can order and receive the collection kit through two options: payment by instalments in 25 months, or payment in a single payment. In the event that the procedure does not have a positive outcome, a refund is always guaranteed, depending on when the service is interrupted. Contact us for more information.
In the (highly unlikely) case where the bank where the samples are stored becomes insolvent, Swiss Stem Cell Science will transfer the samples to another equally accredited facility that will comply with the terms of the original agreement. As a member of a strong prestigous group specialized in stem cells, the samples are safe and will always remain in Switzerland.
There are alternatives to the preservation of cord blood, such as the removal of stem cells from bone marrow and peripheral blood. However, stem cord cells have numerous advantages: they are the youngest and most effective cells found in the human body, and are relatively free of environmental and electromagnetic contamination. Furthermore, the procedure for their collection is non-invasive and immediately available.
If the child had a genetic disease, such as sickle cell anaemia, the stem cells would have the same genetic defect. In the case that the autologous stem cells (from the person themself) could not be used, the cord blood of a brother / sister would be the best option.
It is estimated that around 600 samples were released from private cord blood banks for autologous and allogeneic transplants of a sibling or family member.
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- Email: info@swiss-stem-cells-solutions.com
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